Many properties operate with a multitude of connections to distribution partners:-
- Direct connectivity to Booking & Expedia (and I expect more in the future)
- A channel Manager ex. SiteMinder to connect to all the others
- A GDS / BE representing company like SynXis on behalf of Relais & Châteaux (RC) or Small Luxury Hotels (SLH)

It should be possible when setting up Channel Managers (all of the above) or Distribution partners if this is a better terminology to indicate in the connection if a confirmation should be sent.

I know that most OTA's will not allow for hotels to disallow them sending a confirmation, but it is possible for some.

The current settings for sending confirmations is in the "Stay" settings - but would be better to allocate this option when connecting your distribution partner.